Study group with Laura

24th January at 10.20am to 14.45pm

Today I used several databases and read articles in english in my bioinfomatics course. It is a web course, witch is totally in english, now I am already making my final project in there. In final project we are given a protein, mine is delta 6 desaturase. I made this project today with my study friend Laura. We also discussed in english, because I asked for this english course.

I put here something i wrote today about that enzyme;

Human Delta 6 desaturase

Using: NCBI databace

Gene: FADS2 fatty acid desaturase 2 [ Homo sapiens ]

Gene ID: 9415, updated on 8-Jan-2012

Intruduction for delta  6 desaturase:

Linolenic acid witch is the main dietary essential fatty acid is metalized by the body to important sustances. First step is to make it gammalinolenic acid, this step is slow, rate limiting step, particulary in humans. Delta 6 desaturase is katalyzing enzyme in this reaction. If delta 6 desaturase doesn’t work normally or doesn’t exisist in enough, it causes problems. Deseas linked to this are at least atopic eczema and diametes, witch are exempes of inadequate delta 6 desaturation. 

(David F Horrobin, Fatty acid metabolism in health and disease: the role of delta-6-desaturase, The American Journal of Clinical Nutrition (1993): http://www.ajcn.org/content/57/5/732S.short)

Atopic eczema

Atopic eczema is an inherited form of dermatitis, patients are more susceptible than normal to viral infectins and to allergic reactions of various types. Patiens have high consentrations of immunoglobin E and an elevated rotio of lymphocytes (T-helper to T-suppressor).

(David F Horrobin, Fatty acid metabolism in health and disease: the role of delta-6-desaturase, The American Journal of Clinical Nutrition (1993):http://www.ajcn.org/content/57/5/732S.short)

Diabetes mellitus

Diabets is a cronic disease, where pancreas does not produce enough insulin, or when the body cannot effectively use the insulin it produces. This leads to an increased concentration of glucose in the blood, hyperglycaemia.

(WHO, health topics: http://www.who.int/topics/diabetes_mellitus/en/)

Time:  4 hours 25 minutes
Time in total: 13 hours 10 minutes